Lipid Association of India LAI expert consensus statement on management of dyslipidaemia in Indians 2017 part 2

Dyslipidaemia is widely prevalent and is one of the most important risk factors for atherosclerotic cardiovascular disease (ASCVD). Accordingly, effective management of dyslipidaemia is an important goal for the prevention of ASCVD.Numerous leading international societies have published guidelines for the management of dyslipidaemia but these guidelines are not directly applicable to Indians because of various reasons. Indians have an unusually high prevalence of dyslipidaemia comprising of low high-densitylipoprotein cholesterol (HDL-C), high triglycerides Read More

LAI Expert Consensus Statement on Management

The burden of atherosclerotic cardiovascular disease (ASCVD) in India is alarmingly high and is a cause of concern. Indians are not only at high risk of developing ASCVD but also get the disease at an early age, have a more severe form of the disease, and have poorer outcomes compared with Western populations. Access to health care is also not optimal in India, and the treatment of ASCVD remains expensive. For all these reasons, prevention of ASCVD should take priority, not only from the perspective of governmental perspective of all Indians.    Read More

Assessment of lipid profile in everyone in the age group of 18-20 years

  1. For substantial health benefits, adults should do at least 150 minutes a week of moderate-intensity (eg. brisk walking/dancing), or 75 minutes a week of vigorous-intensity aerobic physical activity (eg. aerobics, running, walking up hill).
  1. A Mediterranean diet can reduce cardiac events by 70%. With a Mediterranean Diet, 90 % of the type 2 diabetes, 80 % of coronary artery disease/heart attacks & 70 % of the strokes can be avoided.
  1. An Indo Mediterranean diet includes fruits, vegetables, whole grains like unpolished rice, whole wheat & millets; fatty fish for nonvegetarians and fenugreek seeds, mustard seeds, flax seeds, soybean oil, mustard oil in vegetarians (as sources of omega 3 fatty acids) and nuts.

Assessment of lipid profile in everyone in the age group of 18-20 years

  1. Instituting therapeutic lifestyle changes decreases an individual’s chances of developing heart problems and decreases the risk of worsening of heart problems in those who already have it.
  1. Regular consumption of fruits and vegetables can decrease an individual’s chances of developing heart problems by 30%.
  1. Physical activity reduces the number of small-dense LDL particles, which are an important cause of heart problems in Indians.
  1. Life style modification plays an important role in raising HDL-C.

Assessment of lipid profile in everyone in the age group of 18-20 years

ABOUT LIPIDSA complete blood lipid profile measures the levels of total cholesterol and other particles such as low density lipoprotein (LDL-cholesterol), high density lipoprotein (HDL-cholesterol) and triglycerides (TG). Of these, HDL is known to be protective against heart problems while high levels of LDL and TGs are associated with development of heart problems such coronary artery disease where the blood supply to the heart is reduced.A triad of high TG accompanied by low HDL-C levels and high LDL-C, is known as atherogenic dyslipidemia, and is an important cause of coronary artery disease. In India,the dyslipidemia triad is seen in a significant part of the  population with elevated TG in 29.5%, low HDL in 72.3% and elevated LDL  in 11.8%.

Assessment of lipid profile in everyone in the age group of 18-20 years

Given a high incidence of cardiovascular disease in Indians, we recommend mandatory screening of blood cholesterol profile or lipid profile at the time of college admission and evaluation of the report by a physician. This will help in early identification of young individuals who could be at high risk of developing heart problems in future and for implementation of effective therapeutic strategies.Everyone should keep LDL-C level around 70mgl/dl in blood for effective prevention of heart diseases irrespective of age??It is important to understand that every 39 mg/dL (1 mmol/L) reduction in serum LDL-C (bad cholesterol), sustained over a period of five years, results in the following:
  • a 10% reduction in all-cause mortality
  • a 20% reduction in coronary mortality
  • a 24% reduction in nonfatal myocardial infarction, and
  • a 24% reduction in need for revascularization procedures.

Cardiovascular Diseases

During the past 40 years, CVD has quadrupled in India .WHO estimates that by 2020 more than 50% of cardiac patients worldwide will be Indians. Up to 40% of the patients are below 45 years of age Prevalence of Coronary artery disease is two times higher in urban population as compared to rural population Patients admitted for acute coronary syndrome [ACS] in India are younger, poorer, sicker and more likely to die than ACS patients in the developed world.
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